Progress in application of electrospinning technology in ophthalmology

Abstract

With widespread application of nanofibers in various industries， electrospinning， as a technology for preparing nanofibers， has also received attention. The nanofiber membrane prepared by electrospinning has excellent advantages in drug loading due to its high specific surface area， high porosity， and easy addition of various components， similar to the extracellular matrix. In current studies， drugs have been loaded into nanofibers， achieving sustained release of drugs. Electrospinning membrane has been applied in the treatment of ocular surface diseases， corneal transplantation， glaucoma， and retinal diseases. Based upon existing evidence， the principle， application， and prospect of electrospinning technology in treating ophthalmic conditions were illustrated in this article.

Keywords

• electrospinning|drug delivery|ocular surface diseases|glaucoma|corneal transplantation|retina|nanofiber