E3S Web of Conferences (Jan 2020)

Correction of cellular immunity with biferon-C in piglets in case of specific prevention of circovirosis and mycoplasmosis

  • Shakhov Aleksey,
  • Shabunin Sergey,
  • Zheynes Mariya

DOI
https://doi.org/10.1051/e3sconf/202022202056
Journal volume & issue
Vol. 222
p. 02056

Abstract

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The results of studying the effect of biferon-C containing recombinant porcine interferons -alpha and -gamma on cellular nonspecific and adaptive immunity in piglets in case of specific prevention of circovirosis and mycoplasmosis are presented. The corrective effect of the drug on cellular immunity was stated, manifested by an increase in the absorption and functional and metabolic activity of phagocytes, the relative and absolute number of T- and B-lymphocytes, T-cells with helper activity and a lower formation of the level of T-suppressors, an increase in the T-helpers/T-suppressors ratio.