Kinkéliba (<i>Combretum micranthum</i>) Leaf Extract Alleviates Skin Inflammation: In Vitro and In Vivo Study

Abstract

Kinkéliba (Combretum micranthum, Seh-Haw in Wolof) is a popular bush tea in West African countries. Although the kinkéliba plant’s leaves have been widely consumed for its nutritional and medicinal properties, its benefits on skin health potential have been practically untouched. In human epidermal primary keratinocytes, vitexin and isovitexin-rich kinkéliba extract treatment significantly (p p p p p p < 0.001), compared with D0. In vitro and in vivo data support a new topical application of the kinkéliba leaf as an effective active ingredient for the treatment of skin inflammation, as well as subsequent barrier dysfunction and inflammaging.

Keywords

• kinkéliba
• <i>Combretum micranthum</i>
• anti-inflammation
• anti-oxidant
• skin repair