Nature Communications (Apr 2022)

A universal deep neural network for in-depth cleaning of single-cell RNA-Seq data

  • Hui Li,
  • Cory R. Brouwer,
  • Weijun Luo

DOI
https://doi.org/10.1038/s41467-022-29576-y
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 11

Abstract

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Single cell RNA sequencing (scRNA-Seq) is widely used in biomedical research. Here the authors develop a novel AI model-AutoClass, which effectively cleans a wide range of noise and artifacts in scRNA-Seq data and improves downstream analyses.