The Role and Mechanism of S1PR5 in Colon Cancer [Retraction]

Abstract

Zhou H, Yin X, Bai F, Liu W, Jiang S, Zhao J. Cancer Manag Res. 2020;12:4759—4775. The Editor-in-chief and Publisher of Cancer Management and Research wish to retract the published article. Concerns were raised of alleged image duplication in Figure 10A Migration panel SIPR5 OE-/IDO1 shRNA- and Figure 10B Invasion panel SIPR5 OE+/IDO1 shRNA+. The authors responded to our queries but were unable to provide a satisfactory explanation for the alleged duplication or provide adequate raw data for the study described. It was determined the findings of the study could not be supported and the decision was made to retract the article. The authors agree with this decision. Our decision-making was informed by our policy on publishing ethics and integrity and the COPE guidelines on retraction. The retracted article will remain online to maintain the scholarly record, but it will be digitally watermarked on each page as “Retracted”. This retraction relates to this paper

Keywords

• s1pr5
• nf-κb
• ido1
• colon cancer