139 Chimeric antigen receptor macrophages (CAR-M) elicit a systemic anti-tumor immune response and synergize with PD1 blockade in immunocompetent mouse models of HER2+ solid tumors

• Daniel Blumenthal,
• Michael Klichinsky,
• Yumi Ohtani,
• Rashid Gabbasov,
• Stefano Pierini,
• Linara Gabitova,
• Thomas Condamine,
• Michael Ball,
• Sascha Abramson,
• Alison Worth,
• Ilyssa Ramos

Affiliations

Daniel Blumenthal

3 Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA

Michael Klichinsky

Carisma Therapeutics, Philadelphia, PA, USA

Yumi Ohtani

Carisma Therapeutics, Philadelphia, PA, USA

Rashid Gabbasov

Carisma Therapeutics, Philadelphia, PA, USA

Stefano Pierini

Carisma Therapeutics, Philadelphia, PA, USA

Linara Gabitova

Carisma Therapeutics, Philadelphia, PA, USA

Thomas Condamine

2Incyte Corporation, Wilmington, DE, USA

Michael Ball

1Institute of Psychiatry, Psychology & Neuroscience, King`s College London, London, UK

Sascha Abramson

3Carisma Therapeutics, Springfield, NJ, USA

Alison Worth

Carisma Therapeutics, Philadelphia, PA, USA

Ilyssa Ramos

Carisma Therapeutics, Philadelphia, PA, USA