The impact of masticatory dysfunction caused by occlusal disharmony on cognitive function
OU Yanzhen,
LI Baosheng,
CAI Qing,
JIANG Jiayang,
JIN Zhuohua,
MENG Weiyan
Affiliations
OU Yanzhen
Oral Implantology Department, School and Hospital of Stomatology, Jilin Provincial Key Laboratory of Tooth Development and Bone Remodeling, Jilin University
LI Baosheng
Oral Implantology Department, School and Hospital of Stomatology, Jilin Provincial Key Laboratory of Tooth Development and Bone Remodeling, Jilin University
CAI Qing
Oral Implantology Department, School and Hospital of Stomatology, Jilin Provincial Key Laboratory of Tooth Development and Bone Remodeling, Jilin University
JIANG Jiayang
Oral Implantology Department, School and Hospital of Stomatology, Jilin Provincial Key Laboratory of Tooth Development and Bone Remodeling, Jilin University
JIN Zhuohua
Oral Implantology Department, School and Hospital of Stomatology, Jilin Provincial Key Laboratory of Tooth Development and Bone Remodeling, Jilin University
MENG Weiyan
Oral Implantology Department, School and Hospital of Stomatology, Jilin Provincial Key Laboratory of Tooth Development and Bone Remodeling, Jilin University
As the world’s population ages, age-related cognitive decline and dementia are becoming important challenges for geriatric care. Despite the ongoing search for solutions to address cognitive decline, effective interventions have not yet been established. There is increasing evidence from clinical, epidemiological, and animal studies that masticatory dysfunction due to occlusal disharmony is a risk factor for cognitive decline and an increased incidence of dementia. The mechanisms may involve altered nutritional intake, decreased cerebral blood flow, chronic stress, and hippocampal morphological function. These findings suggest that maintaining and adequately restoring the entire masticatory system has a positive impact for the prevention of cognitive decline.
