A Mild and Efficient Method for the Syntheses and Regioselective Ring-Opening of Aziridines

Nirnita Chakraborty Ghosal; Sachinta Mahato; Rana Chatterjee; Sougata Santra; Grigory V. Zyryanov; Adinath Majee

doi:10.1055/s-0036-1588809

SynOpen (Mar 2017)

A Mild and Efficient Method for the Syntheses and Regioselective Ring-Opening of Aziridines

Nirnita Chakraborty Ghosal,
Sachinta Mahato,
Rana Chatterjee,
Sougata Santra,
Grigory V. Zyryanov,
Adinath Majee

Affiliations

Nirnita Chakraborty Ghosal: Department of Chemistry, Visva-Bharati (A Central University)
Sachinta Mahato: Department of Chemistry, Visva-Bharati (A Central University)
Rana Chatterjee: Department of Chemistry, Visva-Bharati (A Central University)
Sougata Santra: Department of Organic and Biomolecular Chemistry, Chemical Engineering Institute, Ural Federal University
Grigory V. Zyryanov: Department of Organic and Biomolecular Chemistry, Chemical Engineering Institute, Ural Federal University
Adinath Majee: Department of Chemistry, Visva-Bharati (A Central University)

DOI: https://doi.org/10.1055/s-0036-1588809
Journal volume & issue: Vol. 01, no. 01
pp. 0015 – 0023

Abstract

Read online

Abstract We have developed a new synthetic method for the synthesis of aziridines using Chloramine-T as an effective reagent in the presence of NH2OH·HCl and NaIO4. We found that the same combination of NH2OH·HCl and NaIO4 is also very effective for nucleophilic ring opening of aziridines.

Published in SynOpen

ISSN: 2509-9396 (Online)
Publisher: Georg Thieme Verlag KG
Country of publisher: Germany
LCC subjects: Science: Chemistry
Website: https://doi.org/10.1055/s-00032269

About the journal

Abstract

Keywords