402 Serum cytokine profiling reveals elevated levels of S100A8/A9 and MMP-9 in systemic lupus erythematosus patients with cognitive impairment independently of disease activity and inflammatory markers

• Dorcas Beaton,
• Jiandong Su,
• Zahi Touma,
• Robin Green,
• Patricia Katz,
• Lesley Ruttan,
• May Y Choi,
• Joan Wither,
• Dennisse Bonilla,
• Kathleen Bingham,
• Mahta Kakvan,
• Carolina Muñoz Grajales,
• Michelle L Barraclough,
• Juan P Diaz-Martinez,
• M Carmela Tartaglia,
• Simon Appenzeller

Affiliations

Dorcas Beaton

Mobility Program Clinical Research Unit, St Michael`s Hospital Li Ka Shing Knowledge Institute, Toronto, Ontario, Canada

Jiandong Su

Lupus Clinic, Centre for Prognosis Studies in the Rheumatic Diseases, University Health Network, Toronto, Ontario, Canada

Zahi Touma

Division of Rheumatology, Department of Medicine, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada

Robin Green

Paediatrics and Child Health, University of Pretoria Faculty of Health Sciences, Pretoria, Gauteng, South Africa

Patricia Katz

Department of Medicine, Division of Rheumatology, University of California San Francisco, San Francisco, California, USA

Lesley Ruttan

1 Hull-Ellis Concussion Research Centre, Toronto Rehabilitation Institute, University Health Network, Toronto, Ontario, Canada

May Y Choi

Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada

Joan Wither

1Krembil Research Institute, University Health Network, Toronto, Canada

Dennisse Bonilla

1Krembil Research Institute, University Health Network, Toronto, Canada

Kathleen Bingham

Psychiatry Department, Centre for Mental Health, University Health Network, Toronto, Ontario, Canada

Mahta Kakvan

Centre for Prognosis Studies in Rheumatic Diseases, Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada

Carolina Muñoz Grajales

1Schroeder Arthritis Institute, Krembil Research Institute, University Health Network, Toronto, Canada

Michelle L Barraclough

1Schroeder Arthritis Institute, Krembil Research Institute, University Health Network, Toronto, Canada

Juan P Diaz-Martinez

1Schroeder Arthritis Institute, Krembil Research Institute, University Health Network, Toronto, Canada

M Carmela Tartaglia

5University of Toronto Krembil Neurosciences Centre, Toronto, Canada

Simon Appenzeller

8University of Campinas, São Paulo, Brazil