Nature Communications (Jan 2021)
Duration and key determinants of infectious virus shedding in hospitalized patients with coronavirus disease-2019 (COVID-19)
- Jeroen J. A. van Kampen,
- David A. M. C. van de Vijver,
- Pieter L. A. Fraaij,
- Bart L. Haagmans,
- Mart M. Lamers,
- Nisreen Okba,
- Johannes P. C. van den Akker,
- Henrik Endeman,
- Diederik A. M. P. J. Gommers,
- Jan J. Cornelissen,
- Rogier A. S. Hoek,
- Menno M. van der Eerden,
- Dennis A. Hesselink,
- Herold J. Metselaar,
- Annelies Verbon,
- Jurriaan E. M. de Steenwinkel,
- Georgina I. Aron,
- Eric C. M. van Gorp,
- Sander van Boheemen,
- Jolanda C. Voermans,
- Charles A. B. Boucher,
- Richard Molenkamp,
- Marion P. G. Koopmans,
- Corine Geurtsvankessel,
- Annemiek A. van der Eijk
Affiliations
- Jeroen J. A. van Kampen
- Department of Viroscience, Erasmus MC
- David A. M. C. van de Vijver
- Department of Viroscience, Erasmus MC
- Pieter L. A. Fraaij
- Department of Viroscience, Erasmus MC
- Bart L. Haagmans
- Department of Viroscience, Erasmus MC
- Mart M. Lamers
- Department of Viroscience, Erasmus MC
- Nisreen Okba
- Department of Viroscience, Erasmus MC
- Johannes P. C. van den Akker
- Department of Intensive Care, Erasmus MC
- Henrik Endeman
- Department of Intensive Care, Erasmus MC
- Diederik A. M. P. J. Gommers
- Department of Intensive Care, Erasmus MC
- Jan J. Cornelissen
- Department of Hematology, Erasmus MC
- Rogier A. S. Hoek
- Department of Pulmonary Medicine, Erasmus MC
- Menno M. van der Eerden
- Department of Pulmonary Medicine, Erasmus MC
- Dennis A. Hesselink
- Erasmus MC Transplant Institute
- Herold J. Metselaar
- Erasmus MC Transplant Institute
- Annelies Verbon
- Department of Medical Microbiology and Infectious Diseases, Erasmus MC
- Jurriaan E. M. de Steenwinkel
- Department of Medical Microbiology and Infectious Diseases, Erasmus MC
- Georgina I. Aron
- Department of Viroscience, Erasmus MC
- Eric C. M. van Gorp
- Department of Viroscience, Erasmus MC
- Sander van Boheemen
- Department of Viroscience, Erasmus MC
- Jolanda C. Voermans
- Department of Viroscience, Erasmus MC
- Charles A. B. Boucher
- Department of Viroscience, Erasmus MC
- Richard Molenkamp
- Department of Viroscience, Erasmus MC
- Marion P. G. Koopmans
- Department of Viroscience, Erasmus MC
- Corine Geurtsvankessel
- Department of Viroscience, Erasmus MC
- Annemiek A. van der Eijk
- Department of Viroscience, Erasmus MC
- DOI
- https://doi.org/10.1038/s41467-020-20568-4
- Journal volume & issue
-
Vol. 12,
no. 1
pp. 1 – 6
Abstract
Duration of infectious SARS-CoV-2 shedding is an important measure for improved disease control. Here, the authors use virus cultures of respiratory tract samples from COVID-19 patients and observe a median shedding duration of 8 days and a drop below 5% after 15,2 days post onset of symptoms.