Medicina (Jun 2016)
The tuberculosis recurrence in city of Jundiaí since 2006 to 2011: a clinical and epidemiological profile
Abstract
The TB recurrence occurs when a patient presents current diagnosis of tuberculosis with positive bacteriology ( microscopy or culture) , with history of cured TB with anti -TB drugs. Evaluation of the clinical and epidemiological aspects of TB recurrence is extremely important, because this data is able to guide and clarify the effectiveness of DOTS ( Directly Observed Treatment Short), the pharmacological treatment regimen used and the predisposing factors for recurrence. Objective: Describe some characteristics of clinical and epidemiological profile of tuberculosis recurrence in Jundiaí in the period 2006-2011. Methods: This is a descriptive study, type of survey data from the Officer of the Ministry of health of Brazil named Tbweb. Results: In the period from 2006 to 2011 were reported 34 cases of recurrence, all pacients being residents in the city of Jundiaí. The median age was 51 ± 17.5 years. The serology for human immunodeficiency virus (HIV ) was performed in 34 (100 %) patients and was positive in 10 ( 29.4%) of them. For other comorbidities 6 (17.6%) cases were alcoholics, and 1 (2.9%) , drug user. The quadruple regimen ( rifampicin , isoniazid , pyrazinamide , ethambutol ) drugs was adopted since 2006. The Strategy Directly Observed Treatment ( DOTS) was held in 21 cases ( 61.7 % ) . The pulmonary type was the most common, presenting 82.3 % of cases. Tb laboratory tests were positive in 17 ( 50.0 %) cases of pulmonary involvement , and 6 ( 17.6 %) cases of extrapulmonary involvement. The duration of treatment was on average 6.5 mounths. The pharmacological treatment ended with 29 cases (85.2 %) cured , 2 ( 5.9%) with treatment neglect and 1 (2.9%) death due to tuberculosis. Conclusion: The relapse of TB was more common in HIV-positive patients. The job of the quadruple (rifampicin , isoniazid , pyrazinamide , ethambutol ) schema in the treatment showed no reduction in the number of cases of TB recurrence of this sample. The use of DOTS had no impact on the cases of relapse in the municipality of Jundiaí. However, new studies with longer historical series must be carried out to check their epidemiological significance appropriate
Keywords
