Outcomes of Intravenous Thrombolytic Therapy in Acute Ischemic Stroke

Abstract

Purpose: In this study, we aimed to share our experiences about the efficacy, complications and prognosis of intravenous recombinant tissue plasminogen activator (iv rt-PA) in patients with acute ischaemic stroke in our stroke unit. Materials and Methods: Between September 2018 and December 2021, 39 patients who underwent iv rt-PA in our stroke unit were retrospectively analysed. Demographic characteristics, stroke risk factors, symptom-door, symptom-needle time, NIHSS (National Institutes of Health Stroke Scale) and MRS (Modified Rankin Scale) values of the patients were recorded from their files. Results: Twenty-two patients were female (56.4%) and 17 were male (43.6%). The most common risk factors were hypertension (56.4%) and hyperlipidemia (46.2%). NIHSS scores at admission, 24 h and day 7 were 17.3±5.9, 13.4±8.7, 11.1±10.3, respectively. Cerebral haemorrhage was detected in only 9 (23.1%) of the patients and death was detected in 12 (30.8%). Conclusion: Iv rt-PA treatment is an effective and safe method for acute ischemic stroke. Increasing public awareness and the number of stroke units and centers in stroke treatment will significantly improve success rates to much higher levels.

Keywords

• retrospective
• patient
• treatment success