Nature Communications (Apr 2022)

DNA methylation in newborns conceived by assisted reproductive technology

  • Siri E. Håberg,
  • Christian M. Page,
  • Yunsung Lee,
  • Haakon E. Nustad,
  • Maria C. Magnus,
  • Kristine L. Haftorn,
  • Ellen Ø. Carlsen,
  • William R. P. Denault,
  • Jon Bohlin,
  • Astanand Jugessur,
  • Per Magnus,
  • Håkon K. Gjessing,
  • Robert Lyle

DOI
https://doi.org/10.1038/s41467-022-29540-w
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 12

Abstract

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Timing of assisted reproduction technology (ART) procedures coincides with extensive epigenetic remodeling early after conception. Here the authors identify 176 DNA methylation differences in cord blood of newborns conceived with ART. including genes related to growth, neurodevelopment, and cancer.