Tissue, urine and serum NMR metabolomics dataset from a 5/6 nephrectomy rat model of chronic kidney disease

Munsoor A Hanifa; Martin Skott; Raluca G Maltesen; Bodil S Rasmussen; Søren Nielsen; Jørgen Frøkiær; Troels Ring; Reinhard Wimmer

Data in Brief (Dec 2020)

Tissue, urine and serum NMR metabolomics dataset from a 5/6 nephrectomy rat model of chronic kidney disease

Munsoor A Hanifa,
Martin Skott,
Raluca G Maltesen,
Bodil S Rasmussen,
Søren Nielsen,
Jørgen Frøkiær,
Troels Ring,
Reinhard Wimmer

Affiliations

Munsoor A Hanifa: Department of Chemistry and Bioscience, Aalborg University, 9220 Aalborg, Denmark; Department of Anaesthesia and Intensive Care Medicine, Aalborg University Hospital, 9000 Aalborg, Denmark; Department of Clinical Medicine, Aalborg University, 9000 Aalborg, Denmark
Martin Skott: Department of Urology, Aarhus University Hospital, 8250 Aarhus N, Denmark
Raluca G Maltesen: Department of Anaesthesia and Intensive Care Medicine, Aalborg University Hospital, 9000 Aalborg, Denmark
Bodil S Rasmussen: Department of Anaesthesia and Intensive Care Medicine, Aalborg University Hospital, 9000 Aalborg, Denmark; Department of Clinical Medicine, Aalborg University, 9000 Aalborg, Denmark
Søren Nielsen: 2A Pharma AB, Södergatan 3, 211 34 Malmö, Sweden
Jørgen Frøkiær: Department of Clinical Medicine, Aarhus University, 8200 Aarhus N, Denmark
Troels Ring: Department of Biomedicine, Aarhus University, 8000 Aarhus C, Denmark; The Center for Critical Care Nephrology, Department of Critical Care Medicine, University of Pittsburgh, Pittsburg, PA 15261, United States of America
Reinhard Wimmer: Department of Chemistry and Bioscience, Aalborg University, 9220 Aalborg, Denmark; Corresponding author.

Journal volume & issue: Vol. 33
p. 106567

Abstract

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Serum, urine and tissue from a rat model of chronic kidney disease (CKD) were analysed using nuclear magnetic resonance (NMR) spectroscopy-based metabolomics methods, and compared with samples from sham operated rats. Both urine and serum were sampled at multiple timepoints, and the results have been reported elsewhere (https://doi.org/10.1007/s11306-019-1569-3 [1]). The data could be useful to researchers working with human CKD or rat models of the disease. In addition, several different types of NMR spectra were recorded, including 1D NOESY, CPMG, and 2D J-resolved spectra, and the data could be useful for method comparison and algorithm development, both in terms of NMR spectroscopy and multivariate analysis.

Published in Data in Brief

ISSN: 2352-3409 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Medicine (General): Computer applications to medicine. Medical informatics; Science: Science (General)
Website: http://www.journals.elsevier.com/data-in-brief/

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