JMIR Public Health and Surveillance (Aug 2024)

Association Between P<sub/>articulate Matter Exposure and Preterm Birth in Women With Abnormal Preconception Thyrotropin Levels: Large Cohort Study

  • Ting Xu,
  • Haobo Ni,
  • Xiaoyan Cai,
  • Tingting Dai,
  • Lingxi Wang,
  • Lina Xiao,
  • Qinghui Zeng,
  • Xiaolin Yu,
  • Lu Han,
  • Pi Guo

DOI
https://doi.org/10.2196/53879
Journal volume & issue
Vol. 10
pp. e53879 – e53879

Abstract

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Abstract BackgroundPrior research has linked exposure to particulate matter with an aerodynamic diameter of ≤2.5 μm (PM2.52.5 ObjectiveThis study aimed to assess whether preconception TSH levels modulate the impact of PM2.5 MethodsThis cohort study was conducted in Guangdong, China, as a part of the National Free Pre-Pregnancy Checkups Project. PM2.52.52.5 ResultsA total of 633,516 women who delivered between January 1, 2014, to December 31, 2019, were included. In total, 34,081 (5.4%) of them had abnormal preconception TSH levels. During the entire pregnancy, each 10-μg/m32.52.5 ConclusionsPM2.52.5