Nature Communications (Jul 2019)
An anionic human protein mediates cationic liposome delivery of genome editing proteins into mammalian cells
Abstract
Inefficient delivery of proteins into mammalian cells limits their use in research and therapy. Here, the authors discover that ProTα, a small, intrinsically disordered human protein can facilitate efficient cationic lipid-mediated protein delivery of genome editing proteins into mammalian cells.