Acta Scientiarum: Biological Sciences (May 2011)

<b>Antibacterial activity and chemical composition of essential oil of <em>Lippia microphylla</em> Cham</b> - doi: 10.4025/actascibiolsci.v33i2.5792

  • Fabiola Fernandes Galvão Rodrigues,
  • Henrique Douglas Melo Coutinho,
  • Adriana Rolim Campos,
  • Sidney Gonçalo Lima,
  • José Galberto Martins Costa

DOI
https://doi.org/10.4025/actascibiolsci.v33i2.5792
Journal volume & issue
Vol. 33, no. 2

Abstract

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The essential oil from the fresh leaves of Lippia microphylla Cham. was obtained by hydrodistillation and characterized by gas chromatography-mass spectrometry (GC-MS). Major constituents of the oil were 1.8-cineole (18.12%), β-ocimene (15.20%), bicyclogermacrene (11.63%) and caryophyllene oxide (8.32%). Antimicrobial activity of the oil against Gram-positive and Gram-negative bacteria was determined by gel diffusion method. The oil showed good antibacterial activity against Shigella flexneri, Escherichia coli and Streptococcus pyogenes and very good antibacterial activity against Staphylococcus aureus.

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