IMPACT OF DETOXIFICATION TREATMENT ON WATER AND ELECTROLYTE METABOLISM AT KETOACIDOSIS

Abstract

Diabetes mellitus (DM) refers to one of the largest emerging threats to health in the 21st century which prevalence has been increasing steadily all over the world. Despite the modern methods of diabetes diagnosis and medications, compensation less than 30 % of patients can be achieved. During the lifetime 87 % of people with diabetes have acute complications. That is why the search for the most effective and available ways of treatment to improve electrolyte metabolism and accelerate the withdrawal of patients with decompensated diabetes is very important. The aim of the work – to investigate diabetic ketoacidosis; optimize methods and treatment conditions; investigate the effect of Rehydron Optim on electrolyte balance in diabetic ketoacidosis and compare the therapeutic effectiveness of complex treatment of Rehydron Optim with standard therapy. Materials and Methods. We examined 30 patients aged 18–40 years with acute complications of decompensated diabetes. Results and Discussion. Disbalance in electrolyte compound was revealed in patients with ketoacidosis and was established the acceleration of compensation homeostasis by used in complex treatment Rehydron Optim. Conclusions. The use of Rehydron Optim significantly reduces the frequency of clinical manifestations of ketosis in 24 hours. On the third day of treatment it completely eliminates ketoacidosis in most patients. It is well-tolerated, has a good safety profile, restores electrolytes in the blood, compared to the control group.

Keywords

• цукровий діабет
• кетоацидоз
• електролітний обмін.