Study of the kidney function remaining in kidney donors and its related factors in transplant center of Imam Khomeini hospital, Urmia

Abstract

Introduction: Concerns about the occurrence of premature kidney failure have been expressed a few years after the kidney donation in the donor due to increase in compensatory blood flow in the remaining kidney nephrons. Objectives: This study aimed to study the kidney function remaining in living kidney donors and its related factors. Patients and Methods: Data were collected from 30 kidney donors in Imam Khomeini hospital in Urmia and evaluated using SPSS-22 software. Results: The mean duration of nephrectomy was 36.36 ± 6.22 years. The mean serum creatinine was significantly increased at the time of examination than before donation, and the glomerular filtration rate (GFR) decreased significantly (P<0.001). Male donors (P=0.025) and donors who did not have relative relationship with the recipient (P=0.44) had better kidney function. The renal function at the time of examination was 74.86% amount before donation. The glucose tolerance test (mg/dL 2 hours) of the donors increased significantly at the time of the study compared to the time before donation (P=0.049). Conclusion: The remaining kidney function of the donors has decreased significantly seven years after donation. It seems that kidney donors need more time to excrete excess glucose, so they are far from being over-carbohydrate.

Keywords

• kidney transplantation
• live donors
• glomerular filtration rate