The Henry Reaction in [Bmim][PF6]-based Microemulsions Promoted by Acylase

Abstract

An environmentally-friendly, enzyme-promoted procedure for the Henry reaction was first studied using water-in-[Bmim][PF6] microemulsions as reaction medium. The Amano acylase from Aspergillus oryzae showed better catalytic activity for the addition reactions of nitromethane with a series of aromatic aldehydes, and a highest yield of 90% was obtained.

Keywords

• Henry reaction
• acylase
• water-in-[Bmim][PF6] microemulsion
• enzyme promiscuity