Introduction of the distance methods of genetic counseling for the parents of children with craniofacial microsomia. Determination of the frequency of inheritance of the shape of the auricle

Abstract

Today we are talking about Craniofacial microsomia or First and second branchial arch syndrome (CFM) as the second most common congenital malformation of the maxillofacial area after cleft lip and palate with extremely diverse phenotype and different types. First and second branchial arch syndrome amount to 11% of all defects in the formation of tissues and organs of the maxillofacial area. The aim of our study was to improve the quality of prevention and care for patients with CFM syndrome. Questionnaires developed for parents have included questions for the anamnesis of life and disease, hereditary factors, gestation course, the growth and development of children with such pathology. The data of 18 patients treated at the Department of pediatric maxillofacial surgery of MSMSU were analyzed. During the study exogenous and endogenous factors influencing the development of craniofacial microsomia syndromes (CFM) were identified. It was justified to use the ears of parents as a template of the missing organ of the child within preoperative preparation. It was revealed that the pathology of the urinary system and small abnormalities of the heart cannot be associated with the symptoms of CFM.

Keywords

• краниофациальная микросомия
• коморбидная патология
• экзогенные и эндогенные факторы