Association of BMI with Testosterone in Infertile Males among Local Population

Abstract

Objective To ascertain association of raised BMI with Testosterone levels among infertile males. Methods A cross sectional study was conducted from April 2010 to March 2011. Sample size was 300 males (147 infertile and 153 healthy fertile control subjects) aged 30 and 60 years, selected from the Jinnah Postgraduate Medical Center (JPMC), Aziz Medical Center and Abbasi Shaheed Hospital, Karachi. All the subjects were grouped to BMI criteria (Ascian pacific region for WHO). They were selected by purposive sampling after a detailed medical history and physical examination. Semen analysis was done and blood samples were collected for serum Testosterone levels. Data was analyzed via SPSS 16.0 by using Analysis of Variances (ANOVA) and independent t test to compare the means and to observe sensitivity of tests and to evaluate the significant association with in the group. Results A significant negative correlation existed between Testosterone and BMI .Raised BMI appear to have an association with male infertility with the reduction in Testosterone levels. Conclusion Obesity is confirmed as risk factor for male infertility in local population.

Keywords

• bmi
• male infertility
• testosterone
• azoospermia
• oligospermia