Journal of Research and Innovation for Sustainable Society (Nov 2020)
Potential association of vitamin D in preventing COVID-19
Abstract
This paper presents the role of vitamin D in the body, namely: calcium absorption, maintaining muscle function, but also in strengthening the immune system. Vitamin D exerts its biological functions dependent on vitamin D receptor (VDR), which is a member of the superhuman family of nuclear hormone receptors and clearly expressed in a wide variety of cells. Vitamin D is mainly obtained by synthesizing Vitamin D3 in our skin using ultraviolet light B (UVB) and in small amounts from food sources. Respiratory epithelial cells can convert vitamin D to the active form and that vitamin D metabolites increase the cytokines involved in immunity in response to respiratory viruses. Studies have shown that the most vulnerable population group for COVID - 19 is also the one with the highest vitamin D deficiency.
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