Frontiers in Pharmacology (Jul 2017)

Annual Meeting of the International Society of Cancer Metabolism (ISCaM): Metabolic Networks in Cancer

  • Nicola Baldini,
  • Nicola Baldini,
  • Angelo De Milito,
  • Olivier Feron,
  • Robert J. Gillies,
  • Carine Michiels,
  • Angela M. Otto,
  • Silvia Pastoreková,
  • Stine F. Pedersen,
  • Paolo E. Porporato,
  • Paolo E. Porporato,
  • Pierre Sonveaux,
  • Claudiu T. Supuran,
  • Sofia Avnet

DOI
https://doi.org/10.3389/fphar.2017.00411
Journal volume & issue
Vol. 8

Abstract

Read online

Cancers are metabolic entities wherein cancer cells adapt their metabolism to their oncogenic agenda and microenvironmental influences. Metabolically different cancer cell subpopulations collaborate to optimize nutrient delivery with respect to immediate bioenergetic and biosynthetic needs. They can also metabolically exploit host cells. These metabolic networks are directly linked with cancer progression, treatment resistance and relapse. Conversely, metabolic alterations in cancer are exploited for anticancer therapy, imaging and personalized medicine. These topics were addressed at the 3rd annual meeting of the International Society of Cancer Metabolism (ISCaM) in Brussels, Belgium, on 26–29 October 2016.

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