Downregulation of circ_0037655 impedes glioma formation and metastasis via the regulation of miR-1229-3p/ITGB8 axis

Zou Wenhui; Cao Yalei; Cheng Kai; Li Changyu; Zhu Fu; Yang Shumao; Jin Maolin; Song Shaojun

doi:10.1515/biol-2021-0048

Open Life Sciences (May 2021)

Downregulation of circ_0037655 impedes glioma formation and metastasis via the regulation of miR-1229-3p/ITGB8 axis

Zou Wenhui,
Cao Yalei,
Cheng Kai,
Li Changyu,
Zhu Fu,
Yang Shumao,
Jin Maolin,
Song Shaojun

Affiliations

Zou Wenhui: Department of neurosurgery, Hainan Cancer Hospital, No. 6, Changbin Road, Haikou City, Hainan Province, 570100, China
Cao Yalei: Department of neurosurgery, Hainan Cancer Hospital, No. 6, Changbin Road, Haikou City, Hainan Province, 570100, China
Cheng Kai: Department of neurosurgery, Hainan Cancer Hospital, No. 6, Changbin Road, Haikou City, Hainan Province, 570100, China
Li Changyu: Department of neurosurgery, Hainan Cancer Hospital, No. 6, Changbin Road, Haikou City, Hainan Province, 570100, China
Zhu Fu: Department of neurosurgery, Hainan Cancer Hospital, No. 6, Changbin Road, Haikou City, Hainan Province, 570100, China
Yang Shumao: Department of neurosurgery, Hainan Cancer Hospital, No. 6, Changbin Road, Haikou City, Hainan Province, 570100, China
Jin Maolin: Department of neurosurgery, Hainan Cancer Hospital, No. 6, Changbin Road, Haikou City, Hainan Province, 570100, China
Song Shaojun: Department of neurosurgery, Hainan Cancer Hospital, No. 6, Changbin Road, Haikou City, Hainan Province, 570100, China

DOI: https://doi.org/10.1515/biol-2021-0048
Journal volume & issue: Vol. 16, no. 1
pp. 442 – 454

Abstract

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Glioma is the most frequent, highly aggressive primary intracranial malignant tumor. Circular RNA (circRNA) circ_0037655 has been reported to be a vital regulator in glioma. The different functional mechanism behind circ_0037655 was investigated in the current study.

Published in Open Life Sciences

ISSN: 2391-5412 (Online)
Publisher: De Gruyter
Country of publisher: Poland
LCC subjects: Science: Biology (General)
Website: http://www.degruyter.com/view/j/biol

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