Evaluation of Memory Function in the University Students with Helicobacter pylori Infection in Sanandaj

Abstract

Background and Aim: Helicobacter pylori is one of the most common human infections. Although the association between H.pylori infection and Alzheimer's disease has been suggested in some studies, few studies have dealt with the association between Helicobacter pylori infection and memory function. The aim of this study was to evaluate the memory function in the students with H.pylori infection. Material and Methods: This case-control study was performed in Sanandaj universities. 106 H.pylori positive and 119 H. pylori negative students were compared using Wechsler memory test. In order to analyze the data, independent t-test and multiple regression were used. Results: The results of this study showed that there was no statistically significant relationship between Wechsler memory final score and H.pylori infection (p = 0.24). But there was a statistically significant relationship between the visual memory subscale (p = 0.01) and mental control (p =0.003). By controlling the confounding effect of age, H. pylori had a negative effect on mental control (P = 0.03). Also, male gender (p = 0.02) and Helicobacter pylori infection (p = 0.007) had a negative effect on the visual memory. Conclusion: In our study H.pylori infection was not significantly related to the overall memory function of the individuals, but due to the association of this infection with some subscales of memory, further studies are recommended.

Keywords

• helicobacter pylori
• memory
• cognitive impairment
• wechsler memory test