Generation of integration-free induced pluripotent stem cell line (KSCBi017-A) from peripheral blood mononuclear cells of a healthy male individual

Young Sam Im; Dae Hoon Yoo; Hyung-Eun Kim; Ji Young Oh; Yong-Ou Kim

Stem Cell Research (Dec 2022)

Generation of integration-free induced pluripotent stem cell line (KSCBi017-A) from peripheral blood mononuclear cells of a healthy male individual

Young Sam Im,
Dae Hoon Yoo,
Hyung-Eun Kim,
Ji Young Oh,
Yong-Ou Kim

Affiliations

Young Sam Im: Division of Intractable Diseases Research, Korea National Institute of Health, Osong, Cheongju-si, South Korea
Dae Hoon Yoo: Division of Intractable Diseases Research, Korea National Institute of Health, Osong, Cheongju-si, South Korea
Hyung-Eun Kim: Division of Intractable Diseases Research, Korea National Institute of Health, Osong, Cheongju-si, South Korea
Ji Young Oh: Division of Intractable Diseases Research, Korea National Institute of Health, Osong, Cheongju-si, South Korea
Yong-Ou Kim: Corresponding author.; Division of Intractable Diseases Research, Korea National Institute of Health, Osong, Cheongju-si, South Korea

Journal volume & issue: Vol. 65
p. 102965

Abstract

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A human induced pluripotent stem cell (hiPSC) line, KSCBi017-A, was generated from a 50-year-old male individual using non-integrating episomal vectors expressing reprogramming factors. The generated hiPSCs were integration-free, expressed pluripotency markers, exhibited the potential for differentiation into three germ layers in vivo, and maintained the normal karyotype. This cell line can be used as a control for a disease model and is available from Korea National Stem Cell Bank.

Published in Stem Cell Research

ISSN: 1873-5061 (Print); 1876-7753 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Science: Biology (General)
Website: https://www.journals.elsevier.com/stem-cell-research

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