Thymic stromal lymphopoietin in dermatological diseases

Abstract

Thymic stromal lymphopoietin is an epithelial cell-derived cytokine expressed in gut, lungs, skin, and thymus. It affects both the local dermal dendritic cells (DCs) and the circulating myeloid DCs. It has important roles in the pathogenesis of many dermatological diseases and may be correlated with disease activity. In this review, its role in the pathogenesis of some dermatological diseases was illustrated.

Keywords

• atopic dermatitis
• lichen planus
• mycosis fungoides
• psoriasis
• thymic stromal lymphopoietin