Nature Communications (Mar 2022)

Protein-based SARS-CoV-2 spike vaccine booster increases cross-neutralization against SARS-CoV-2 variants of concern in non-human primates

  • Vincent Pavot,
  • Catherine Berry,
  • Michael Kishko,
  • Natalie G. Anosova,
  • Dean Huang,
  • Tim Tibbitts,
  • Alice Raillard,
  • Sylviane Gautheron,
  • Cindy Gutzeit,
  • Marguerite Koutsoukos,
  • Roman M. Chicz,
  • Valerie Lecouturier

DOI
https://doi.org/10.1038/s41467-022-29219-2
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 9

Abstract

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Emerging SARS-CoV-2 variants of concern (VOCs) raise questions on vaccine effectiveness. Here, the authors show that an adjuvanted protein-based SARS-CoV-2 spike vaccine booster increases cross-neutralization of VOC, including omicron, in non-human primates.