Sotos syndrome (cerebral gigantism): analysis of 8 cases

Abstract

Sotos syndrome or cerebral gigantism is characterized by macrocephaly, overgrowth, mental retardation and central nervous system abnormalities. Congenital heart defects may be present. We report 8 patients with this syndrome and relate their clinical features, neuroimaging and echocardiographic findings.

Keywords

• Sotos syndrome
• cerebral gigantism
• macrocephaly
• mental retardation