CD3 and CD20 Expression in Titanium  Zirconia Peri-Implant Soft Tissues: A Human Study

F. Bambini; A. Santarelli; G. Marzo; C. Rubini; G. Orsini; D. Di Iorio; L. Lo Russo; L. Lo Muzio

doi:10.1177/1721727X1301100133

European Journal of Inflammation (Jan 2013)

CD3 and CD20 Expression in Titanium Zirconia Peri-Implant Soft Tissues: A Human Study

F. Bambini,
A. Santarelli,
G. Marzo,
C. Rubini,
G. Orsini,
D. Di Iorio,
L. Lo Russo,
L. Lo Muzio

Affiliations

F. Bambini: Department of Clinical Special is tic and Stomatological Sciences, Marche Polytechnic University, Ancona, Italy
A. Santarelli: Department of Clinical Special is tic and Stomatological Sciences, Marche Polytechnic University, Ancona, Italy
G. Marzo: Department of Surgical Sciences, L'Aquila University, L'Aquila, Italy
C. Rubini: Department of Pathologic Anatomy and Histopathology, Marche Polytechnic University, Ancona, Italy
G. Orsini: Department of Clinical Special is tic and Stomatological Sciences, Marche Polytechnic University, Ancona, Italy
D. Di Iorio: Department of Surgical Sciences, Chieti University, Chieti, Italy
L. Lo Russo: Department of Surgical Sciences, Foggia University, Foggia, Italy
L. Lo Muzio: Department of Surgical Sciences, Foggia University, Foggia, Italy

DOI: https://doi.org/10.1177/1721727X1301100133
Journal volume & issue: Vol. 11

Abstract

Read online

The aim of this study was to investigate the presence of an inflammatory infiltrate in the peri-implant soft tissue of single-implant crowns supported by either zirconia or titanium abutments in healthy subjects. Serial sections from formalin-fixed, paraffin-embedded blocks from peri-implant mucosa of 25 patients were immunohistochemically analyzed for CD3 and CD20 lymphocyte marker expression. The results showed that levels of T cells (CD3) were higher around zirconia than titanium abutments (p<0.05). On the contrary, the levels of B cells (CD20) were found higher around titanium abutment in comparison with the zirconia abutment. These differences were statistically significant (p<0.05).

Published in European Journal of Inflammation

ISSN: 1721-727X (Print); 2058-7392 (Online)
Publisher: SAGE Publishing
Country of publisher: United Kingdom
LCC subjects: Medicine
Website: https://journals.sagepub.com/home/eji

About the journal