Pelargonidin ameliorates MCAO-induced cerebral ischemia/reperfusion injury in rats by the action on the Nrf2/HO-1 pathway

Fu Kong; Chen Miancong; Zheng Hua; Li Chuanzi; Yang Fan; Niu Qian

doi:10.1515/tnsci-2021-0006

Translational Neuroscience (Jan 2021)

Pelargonidin ameliorates MCAO-induced cerebral ischemia/reperfusion injury in rats by the action on the Nrf2/HO-1 pathway

Fu Kong,
Chen Miancong,
Zheng Hua,
Li Chuanzi,
Yang Fan,
Niu Qian

Affiliations

Fu Kong: Department of Radiology, The Second Affiliated Hospital, Hainan Medical University, Haikou, 570311, China
Chen Miancong: Department of Critical Care Medicine, The First Affiliated Hospital of Hainan Medical University, Haikou, 570102, China
Zheng Hua: Department of Radiology, The Second Affiliated Hospital, Hainan Medical University, Haikou, 570311, China
Li Chuanzi: Department of Radiology, The Second Affiliated Hospital, Hainan Medical University, Haikou, 570311, China
Yang Fan: Office of Acupuncture Clinical, College of Traditional Chinese Medicine, Hainan Medical University, No. 3, Xueyuan Road, Longhua District, Haikou, 571199, China
Niu Qian: Office of Acupuncture Clinical, College of Traditional Chinese Medicine, Hainan Medical University, No. 3, Xueyuan Road, Longhua District, Haikou, 571199, China

DOI: https://doi.org/10.1515/tnsci-2021-0006
Journal volume & issue: Vol. 12, no. 1
pp. 020 – 031

Abstract

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Morbidity and mortality remain high for ischemic stroke victims, and at present these patients lack effective neuroprotective agents, which improve the cure rate. In recent years, studies have shown that pelargonidin has many biological actions. However, few studies are available regarding the pelargonidin treatment of cerebral ischemia.

Published in Translational Neuroscience

ISSN: 2081-6936 (Online)
Publisher: De Gruyter
Country of publisher: Poland
LCC subjects: Medicine: Internal medicine: Neurosciences. Biological psychiatry. Neuropsychiatry
Website: http://www.degruyter.com/view/j/tnsci

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