Symptom-based early-stage differentiation between SARS-CoV-2 versus other respiratory tract infections—Upper Silesia pilot study

Justyna Mika; Joanna Tobiasz; Joanna Zyla; Anna Papiez; Małgorzata Bach; Aleksandra Werner; Michał Kozielski; Mateusz Kania; Aleksandra Gruca; Damian Piotrowski; Barbara Sobala-Szczygieł; Bożena Włostowska; Paweł Foszner; Marek Sikora; Joanna Polanska; Jerzy Jaroszewicz

doi:10.1038/s41598-021-93046-6

Scientific Reports (Jun 2021)

Symptom-based early-stage differentiation between SARS-CoV-2 versus other respiratory tract infections—Upper Silesia pilot study

Justyna Mika,
Joanna Tobiasz,
Joanna Zyla,
Anna Papiez,
Małgorzata Bach,
Aleksandra Werner,
Michał Kozielski,
Mateusz Kania,
Aleksandra Gruca,
Damian Piotrowski,
Barbara Sobala-Szczygieł,
Bożena Włostowska,
Paweł Foszner,
Marek Sikora,
Joanna Polanska,
Jerzy Jaroszewicz

Affiliations

Justyna Mika: Department of Data Science and Engineering, Silesian University of Technology
Joanna Tobiasz: Department of Data Science and Engineering, Silesian University of Technology
Joanna Zyla: Department of Data Science and Engineering, Silesian University of Technology
Anna Papiez: Department of Data Science and Engineering, Silesian University of Technology
Małgorzata Bach: Department of Applied Informatics, Silesian University of Technology
Aleksandra Werner: Department of Applied Informatics, Silesian University of Technology
Michał Kozielski: Department of Computer Networks and Systems, Silesian University of Technology
Mateusz Kania: Department of Graphics, Computer Vision and Digital Systems, Silesian University of Technology
Aleksandra Gruca: Department of Computer Networks and Systems, Silesian University of Technology
Damian Piotrowski: Department of Infectious Diseases and Hepatology, Medical University of Silesia
Barbara Sobala-Szczygieł: Department of Infectious Diseases and Hepatology, Medical University of Silesia
Bożena Włostowska: Department of Infectious Diseases and Hepatology, Medical University of Silesia
Paweł Foszner: Department of Graphics, Computer Vision and Digital Systems, Silesian University of Technology
Marek Sikora: Department of Computer Networks and Systems, Silesian University of Technology
Joanna Polanska: Department of Data Science and Engineering, Silesian University of Technology
Jerzy Jaroszewicz: Department of Infectious Diseases and Hepatology, Medical University of Silesia

DOI: https://doi.org/10.1038/s41598-021-93046-6
Journal volume & issue: Vol. 11, no. 1
pp. 1 – 13

Abstract

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Abstract In the DECODE project, data were collected from 3,114 surveys filled by symptomatic patients RT-qPCR tested for SARS-CoV-2 in a single university centre in March-September 2020. The population demonstrated balanced sex and age with 759 SARS-CoV-2( +) patients. The most discriminative symptoms in SARS-CoV-2( +) patients at early infection stage were loss of taste/smell (OR = 3.33, p 38℃ with cough was most frequent in men (20%), while loss of taste/smell with cough in women (17%). For younger people, taste/smell impairment is sufficient to characterise infection, whereas in older patients co-occurrence of fever and cough is necessary. The presented study objectifies the single symptoms and interactions significance in COVID-19 diagnoses and demonstrates diverse symptomatology in patient groups.

Published in Scientific Reports

ISSN: 2045-2322 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Medicine; Science
Website: https://www.nature.com/srep/

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