Obstructive Sleep Apnea and Cancer

Abstract

Obstructive sleep apnea (OSA) is a common disorder which is associated with increased morbidity and mortality. There is growing evidence that patients with OSA have higher incidence of cancer, accelerated progression and cancer mortality. Intermittent hypoxia, oxidative stress and sleep fragmentation are hold responsible for cancer development.

Keywords

• Obstructive sleep apnea
• cancer
• intermittant hypoxi
• oxidative stress
• sleep fragmentation
• inflammation