Forensic medicine has been designated as a first-level discipline, presenting new opportunities and challenges for the development of forensic medicine. Since the 1980s, the establishment of forensic medicine discipline and the cultivation of high-level forensic talents have become hot topics in the development of forensic medicine in China. Since the 13th Five-Year Plan, the forensic team of Shanxi Medical University has been aiming at the forefront, proposing the development goals of “Five First-class” and the discipline development path “Six Major Achievements”. It has selected benchmark disciplines, identified gaps in disciplinary development, unified thoughts, formulated completion timelines, concentrated superior resources, assigned tasks to individuals, and created an “Organized Fill-in-the-Blank Format” forensic medicine discipline construction model with the characteristics of the new era. The construction model of forensic medicine has achieved good results in the goals, discipline framework, scientific research, talent cultivation, discipline team and platform construction, forming a relatively complete discipline construction and management system, and accumulating valuable experience for the construction of first-level discipline and high-level talent cultivation of forensic medicine.