Nature Communications (Nov 2022)
Biotechnologically produced chitosans with nonrandom acetylation patterns differ from conventional chitosans in properties and activities
Abstract
Degree of polymerisation, fraction and pattern of acetylation change the material and biological properties of chitosan. Here, the authors show that enzymes can N-acetylate fully deacetylated chitosan to replicate the natural control over acetylation pattern not found in chemically produced chitosan allowing more control over properties.