Journal of Synchrotron Radiation (May 2025)

Current and future perspectives for structural biology at the Grenoble EPN campus: a comprehensive overview

  • Andrew A. McCarthy,
  • Shibom Basu,
  • Florent Bernaudat,
  • Matthew P. Blakeley,
  • Matthew W. Bowler,
  • Philippe Carpentier,
  • Gregory Effantin,
  • Sylvain Engilberge,
  • David Flot,
  • Frank Gabel,
  • Lukas Gajdos,
  • Jos J. A. G. Kamps,
  • Eaazhisai Kandiah,
  • Romain Linares,
  • Anne Martel,
  • Igor Melnikov,
  • Estelle Mossou,
  • Christoph Mueller-Dieckmann,
  • Max Nanao,
  • Didier Nurizzo,
  • Petra Pernot,
  • Alexander Popov,
  • Antoine Royant,
  • Daniele de Sanctis,
  • Guy Schoehn,
  • Romain Talon,
  • Mark D. Tully,
  • Montserrat Soler-Lopez

DOI
https://doi.org/10.1107/S1600577525002012
Journal volume & issue
Vol. 32, no. 3
pp. 577 – 594

Abstract

Read online

The European Photon and Neutron campus in Grenoble is a unique site, encompassing the European Synchrotron Radiation Facility Extremely Brilliant Source, the Institut Laue–Langevin, the European Molecular Biology Laboratory and the Institut de Biologie Structurale. Here, we present an overview of the structural biology beamlines, instruments and support facilities available on the EPN campus. These include advanced macromolecular crystallography using neutrons or X-rays, small-angle X-ray or neutron scattering, cryogenic electron microscopy, and spectroscopy. These highly complementary experimental approaches support cutting-edge research for integrated structural biology in our large user community. This article emphasizes our significant contributions to the field, outlines current advancements made and provides insights into our future prospects, offering readers a comprehensive understanding of the EPN campus's role in advancing integrated structural biology research.

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