Journal of Synchrotron Radiation (May 2025)
Current and future perspectives for structural biology at the Grenoble EPN campus: a comprehensive overview
- Andrew A. McCarthy,
- Shibom Basu,
- Florent Bernaudat,
- Matthew P. Blakeley,
- Matthew W. Bowler,
- Philippe Carpentier,
- Gregory Effantin,
- Sylvain Engilberge,
- David Flot,
- Frank Gabel,
- Lukas Gajdos,
- Jos J. A. G. Kamps,
- Eaazhisai Kandiah,
- Romain Linares,
- Anne Martel,
- Igor Melnikov,
- Estelle Mossou,
- Christoph Mueller-Dieckmann,
- Max Nanao,
- Didier Nurizzo,
- Petra Pernot,
- Alexander Popov,
- Antoine Royant,
- Daniele de Sanctis,
- Guy Schoehn,
- Romain Talon,
- Mark D. Tully,
- Montserrat Soler-Lopez
Affiliations
- Andrew A. McCarthy
- European Molecular Biology Laboratory (EMBL), Grenoble, France
- Shibom Basu
- European Molecular Biology Laboratory (EMBL), Grenoble, France
- Florent Bernaudat
- European Synchrotron Radiation Facility (ESRF), Grenoble, France
- Matthew P. Blakeley
- Institut Laue–Langevin (ILL), Grenoble, France
- Matthew W. Bowler
- European Molecular Biology Laboratory (EMBL), Grenoble, France
- Philippe Carpentier
- European Synchrotron Radiation Facility (ESRF), Grenoble, France
- Gregory Effantin
- Univ. Grenoble Alpes, CNRS, CEA, Institut de Biologie Structurale (IBS), Grenoble, France
- Sylvain Engilberge
- Univ. Grenoble Alpes, CNRS, CEA, Institut de Biologie Structurale (IBS), Grenoble, France
- David Flot
- European Synchrotron Radiation Facility (ESRF), Grenoble, France
- Frank Gabel
- Institut Laue–Langevin (ILL), Grenoble, France
- Lukas Gajdos
- Institut Laue–Langevin (ILL), Grenoble, France
- Jos J. A. G. Kamps
- European Synchrotron Radiation Facility (ESRF), Grenoble, France
- Eaazhisai Kandiah
- European Synchrotron Radiation Facility (ESRF), Grenoble, France
- Romain Linares
- European Molecular Biology Laboratory (EMBL), Grenoble, France
- Anne Martel
- Institut Laue–Langevin (ILL), Grenoble, France
- Igor Melnikov
- European Synchrotron Radiation Facility (ESRF), Grenoble, France
- Estelle Mossou
- European Synchrotron Radiation Facility (ESRF), Grenoble, France
- Christoph Mueller-Dieckmann
- European Synchrotron Radiation Facility (ESRF), Grenoble, France
- Max Nanao
- European Synchrotron Radiation Facility (ESRF), Grenoble, France
- Didier Nurizzo
- European Synchrotron Radiation Facility (ESRF), Grenoble, France
- Petra Pernot
- European Synchrotron Radiation Facility (ESRF), Grenoble, France
- Alexander Popov
- European Synchrotron Radiation Facility (ESRF), Grenoble, France
- Antoine Royant
- European Synchrotron Radiation Facility (ESRF), Grenoble, France
- Daniele de Sanctis
- European Synchrotron Radiation Facility (ESRF), Grenoble, France
- Guy Schoehn
- Univ. Grenoble Alpes, CNRS, CEA, Institut de Biologie Structurale (IBS), Grenoble, France
- Romain Talon
- European Synchrotron Radiation Facility (ESRF), Grenoble, France
- Mark D. Tully
- European Synchrotron Radiation Facility (ESRF), Grenoble, France
- Montserrat Soler-Lopez
- European Synchrotron Radiation Facility (ESRF), Grenoble, France
- DOI
- https://doi.org/10.1107/S1600577525002012
- Journal volume & issue
-
Vol. 32,
no. 3
pp. 577 – 594
Abstract
The European Photon and Neutron campus in Grenoble is a unique site, encompassing the European Synchrotron Radiation Facility Extremely Brilliant Source, the Institut Laue–Langevin, the European Molecular Biology Laboratory and the Institut de Biologie Structurale. Here, we present an overview of the structural biology beamlines, instruments and support facilities available on the EPN campus. These include advanced macromolecular crystallography using neutrons or X-rays, small-angle X-ray or neutron scattering, cryogenic electron microscopy, and spectroscopy. These highly complementary experimental approaches support cutting-edge research for integrated structural biology in our large user community. This article emphasizes our significant contributions to the field, outlines current advancements made and provides insights into our future prospects, offering readers a comprehensive understanding of the EPN campus's role in advancing integrated structural biology research.
Keywords
- structural biology
- grenoble epn campus
- fourth-generation synchrotrons
- macromolecular crystallography