International Journal of Public Health (Jun 2023)
Time-Trends in Air Pollution Impact on Health in Italy, 1990–2019: An Analysis From the Global Burden of Disease Study 2019
- Sara Conti,
- Carla Fornari,
- Pietro Ferrara,
- Pietro Ferrara,
- Ippazio C. Antonazzo,
- Fabiana Madotto,
- Eugenio Traini,
- Miriam Levi,
- Achille Cernigliaro,
- Achille Cernigliaro,
- Benedetta Armocida,
- Nicola L. Bragazzi,
- Ennio Cadum,
- Michele Carugno,
- Michele Carugno,
- Giacomo Crotti,
- Silvia Deandrea,
- Paolo A. Cortesi,
- Davide Guido,
- Ivo Iavicoli,
- Sergio Iavicoli,
- Carlo La Vecchia,
- Paolo Lauriola,
- Paola Michelozzi,
- Salvatore Scondotto,
- Massimo Stafoggia,
- Francesco S. Violante,
- Cristiana Abbafati,
- Luciana Albano,
- Francesco Barone-Adesi,
- Antonio Biondi,
- Cristina Bosetti,
- Danilo Buonsenso,
- Danilo Buonsenso,
- Giulia Carreras,
- Giulio Castelpietra,
- Giulio Castelpietra,
- Alberico Catapano,
- Alberico Catapano,
- Maria S. Cattaruzza,
- Barbara Corso,
- Giovanni Damiani,
- Giovanni Damiani,
- Francesco Esposito,
- Silvano Gallus,
- Davide Golinelli,
- Simon I. Hay,
- Simon I. Hay,
- Gaetano Isola,
- Caterina Ledda,
- Stefania Mondello,
- Paolo Pedersini,
- Umberto Pensato,
- Norberto Perico,
- Giuseppe Remuzzi,
- Francesco Sanmarchi,
- Rocco Santoro,
- Biagio Simonetti,
- Biagio Simonetti,
- Brigid Unim,
- Marco Vacante,
- Massimiliano Veroux,
- Jorge H. Villafañe,
- Lorenzo Monasta,
- Lorenzo G. Mantovani,
- Lorenzo G. Mantovani
Affiliations
- Sara Conti
- Research Center on Public Health, University of Milan Bicocca, Monza, Italy
- Carla Fornari
- Research Center on Public Health, University of Milan Bicocca, Monza, Italy
- Pietro Ferrara
- Research Center on Public Health, University of Milan Bicocca, Monza, Italy
- Pietro Ferrara
- Laboratory of Public Health, Auxologico Research Hospital—IRCCS, Milan, Italy
- Ippazio C. Antonazzo
- Research Center on Public Health, University of Milan Bicocca, Monza, Italy
- Fabiana Madotto
- Dipartimento di Anestesia, Rianimazione ed Emergenza Urgenza, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milano, Italy
- Eugenio Traini
- Institute for Risk Assessment Sciences (IRAS), Utrecht University, Utrecht, Netherlands
- Miriam Levi
- Epidemiology Unit, Department of Prevention, Central Tuscany Local Health Authority, Florence, Italy
- Achille Cernigliaro
- Health Activities and Epidemiological Observatory Department, Health Authority Sicily Region, Parlemo, Italy
- Achille Cernigliaro
- Clinical Pathology Complex Hospital Unit, Health Authority Trapani Province, Trapani, Italy
- Benedetta Armocida
- Department of Cardiovascular, Endocrine-Metabolic Disease and Aging, National Institute of Health (ISS), Rome, Italy
- Nicola L. Bragazzi
- Laboratory for Industrial and Applied Mathematics (LIAM), Department of Mathematics and Statistics, Faculty of Science, York University, Toronto, ON, Canada
- Ennio Cadum
- 0Department of Hygiene and Health Prevention and Complex Operative Unit Environmental Health and Innovative Projects, Health Protection Agency, Pavia, Italy
- Michele Carugno
- 1Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy
- Michele Carugno
- 2Epidemiology Unit, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy
- Giacomo Crotti
- 3Servizio Epidemiologico Aziendale, Agenzia di Tutela della Salute di Bergamo, Bergamo, Italy
- Silvia Deandrea
- 0Department of Hygiene and Health Prevention and Complex Operative Unit Environmental Health and Innovative Projects, Health Protection Agency, Pavia, Italy
- Paolo A. Cortesi
- Research Center on Public Health, University of Milan Bicocca, Monza, Italy
- Davide Guido
- 4Neurology, Public Health and Disability Unit, Carlo Besta Neurological Institute, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy
- Ivo Iavicoli
- 5Department of Public Health, University of Naples Federico II, Naples, Italy
- Sergio Iavicoli
- 6Department of Occupational and Environmental Medicine Epidemiology and Hygiene, Italian National Workers Compensation Authority (IIL), Monteporzio Catone, Italy
- Carlo La Vecchia
- 1Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy
- Paolo Lauriola
- 7International Network of Public Health and Environment Tracking (INPHET), Milan, Italy
- Paola Michelozzi
- 8Department of Epidemiology, Lazio Region Health Authority (ASL RM1), Rome, Italy
- Salvatore Scondotto
- Health Activities and Epidemiological Observatory Department, Health Authority Sicily Region, Parlemo, Italy
- Massimo Stafoggia
- 8Department of Epidemiology, Lazio Region Health Authority (ASL RM1), Rome, Italy
- Francesco S. Violante
- 9Occupational Health Unit, Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy
- Cristiana Abbafati
- 0Department of Juridical and Economic Studies, Faculty of Law, Sapienza University of Rome, Rome, Italy
- Luciana Albano
- 1Department of Experimental Medicine, University of Campania Luigi Vanvitelli, Naples, Italy
- Francesco Barone-Adesi
- 2Department of Translational Medicine, University of Eastern Piedmont, Novara, Italy
- Antonio Biondi
- 3Department of General Surgery and Medical-Surgical Specialties, University of Catania, Catania, Italy
- Cristina Bosetti
- 4Department of Oncology, Mario Negri Pharmacological Research Institute (IRCCS), Milano, Italy
- Danilo Buonsenso
- 5Department of Woman and Child Health and Public Health, Fondazione Policlinico Universitario A. Gemelli IRCCS (Agostino Gemelli University Polyclinic IRCCS), Rome, Italy
- Danilo Buonsenso
- 6Global Health Research Institute, Università Cattolica del Sacro Cuore (Catholic University of Sacred Heart), Rome, Italy
- Giulia Carreras
- 7Institute for Cancer Research, Prevention and Clinical Network (ISPRO), Florence, Italy
- Giulio Castelpietra
- 8Department of Medicine, University of Udine, Udine, Italy
- Giulio Castelpietra
- 9Department of Mental Health, Healthcare Agency “Friuli Occidentale”, Pordenone, Italy
- Alberico Catapano
- 0Department of Pharmacological and Biomolecular Sciences, University of Milan, Milan, Italy
- Alberico Catapano
- 1MultiMedica, IRCCS, Sesto San Giovanni, Italy
- Maria S. Cattaruzza
- 2Department of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy
- Barbara Corso
- 3Institute of Neuroscience, National Research Council (CNR), Pisa, Italy
- Giovanni Damiani
- 4IRCCS Istituto Ortopedico Galeazzi (Galeazzi Orthopedic Institute IRCCS), University of Milan, Milan, Italy
- Giovanni Damiani
- 5Department of Dermatology, Case Western Reserve University, Cleveland, OH, United States
- Francesco Esposito
- 6Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy
- Silvano Gallus
- 7Department of Environmental Health Sciences, Mario Negri Institute for Pharmacological Research, Milan, Italy
- Davide Golinelli
- 6Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy
- Simon I. Hay
- 8Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, United States
- Simon I. Hay
- 9Department of Health Metrics Sciences, School of Medicine, University of Washington, Seattle, WA, United States
- Gaetano Isola
- 3Department of General Surgery and Medical-Surgical Specialties, University of Catania, Catania, Italy
- Caterina Ledda
- 0Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy
- Stefania Mondello
- 1Department of Biomedical and Dental Sciences and Morphofunctional Imaging, Messina University, Messina, Italy
- Paolo Pedersini
- 2Clinical Research Department, IRCCS Fondazione Don Carlo Gnocchi, Milan, Italy
- Umberto Pensato
- 3Department of Neurology, IRCCS Humanitas Research Hospital, Milan, Italy
- Norberto Perico
- 4Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy
- Giuseppe Remuzzi
- 4Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy
- Francesco Sanmarchi
- 6Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy
- Rocco Santoro
- 5Daccude, Todi, Italy
- Biagio Simonetti
- 6Department of Law, Economics, Management and Quantitative Methods, University of Sannio, Benevento, Italy
- Biagio Simonetti
- 7WSB University in Gdańsk, Gdańsk, Poland
- Brigid Unim
- Department of Cardiovascular, Endocrine-Metabolic Disease and Aging, National Institute of Health (ISS), Rome, Italy
- Marco Vacante
- 4Department of Oncology, Mario Negri Pharmacological Research Institute (IRCCS), Milano, Italy
- Massimiliano Veroux
- 8Department of Medical, Surgical Sciences and Advanced Technologies, University of Catania, Catania, Italy
- Jorge H. Villafañe
- 2Clinical Research Department, IRCCS Fondazione Don Carlo Gnocchi, Milan, Italy
- Lorenzo Monasta
- 9Clinical Epidemiology and Public Health Research Unit, Burlo Garofolo Institute for Maternal and Child Health, Trieste, Italy
- Lorenzo G. Mantovani
- Research Center on Public Health, University of Milan Bicocca, Monza, Italy
- Lorenzo G. Mantovani
- Laboratory of Public Health, Auxologico Research Hospital—IRCCS, Milan, Italy
- DOI
- https://doi.org/10.3389/ijph.2023.1605959
- Journal volume & issue
-
Vol. 68
Abstract
Objectives: We explored temporal variations in disease burden of ambient particulate matter 2.5 μm or less in diameter (PM2.5) and ozone in Italy using estimates from the Global Burden of Disease Study 2019.Methods: We compared temporal changes and percent variations (95% Uncertainty Intervals [95% UI]) in rates of disability adjusted life years (DALYs), years of life lost, years lived with disability and mortality from 1990 to 2019, and variations in pollutant-attributable burden with those in the overall burden of each PM2.5- and ozone-related disease.Results: In 2019, 467,000 DALYs (95% UI: 371,000, 570,000) were attributable to PM2.5 and 39,600 (95% UI: 18,300, 61,500) to ozone. The crude DALY rate attributable to PM2.5 decreased by 47.9% (95% UI: 10.3, 65.4) from 1990 to 2019. For ozone, it declined by 37.0% (95% UI: 28.9, 44.5) during 1990–2010, but it increased by 44.8% (95% UI: 35.5, 56.3) during 2010–2019. Age-standardized rates declined more than crude ones.Conclusion: In Italy, the burden of ambient PM2.5 (but not of ozone) significantly decreased, even in concurrence with population ageing. Results suggest a positive impact of air quality regulations, fostering further regulatory efforts.
Keywords
