Phenolic Compounds of the Medicinal Plants in an Anthropogenically Transformed Environment
Natalya Vinogradova,
Elena Vinogradova,
Victor Chaplygin,
Saglara Mandzhieva,
Pradeep Kumar,
Vishnu D. Rajput,
Tatiana Minkina,
Chandra Shekhar Seth,
Marina Burachevskaya,
Dionise Lysenko,
Rupesh Kumar Singh
Affiliations
Natalya Vinogradova
Department of Management, Economics of Pharmacy, Pharmacognosy and Pharmaceutical Technology, Federal State Budgetary Educational Institution of Higher Professional Education, M. Gorky Donetsk State Medical University, 283003 Donetsk, Russia
Elena Vinogradova
Laboratory of Dendrology of the Federal State Budgetary Scientific Institution “Donetsk Botanical Garden”, 283001 Donetsk, Russia
Victor Chaplygin
Academy of Biology and Biotechnology, Southern Federal University, 344006 Rostov-on-Don, Russia
Saglara Mandzhieva
Academy of Biology and Biotechnology, Southern Federal University, 344006 Rostov-on-Don, Russia
Pradeep Kumar
Department of Botany, Banaras Hindu University, Varanasi 221005, India
Vishnu D. Rajput
Academy of Biology and Biotechnology, Southern Federal University, 344006 Rostov-on-Don, Russia
Tatiana Minkina
Academy of Biology and Biotechnology, Southern Federal University, 344006 Rostov-on-Don, Russia
Chandra Shekhar Seth
Department of Botany, University of Delhi, New Delhi 110007, India
Marina Burachevskaya
Academy of Biology and Biotechnology, Southern Federal University, 344006 Rostov-on-Don, Russia
Dionise Lysenko
Faculty of Pharmacy, Saint Petersburg State Chemical and Pharmaceutical University, 197022 St. Petersburg, Russia
Rupesh Kumar Singh
Centre of Molecular and Environmental Biology, Department of Biology, University of Minho, 4704-553 Braga, Portugal
In this article, the impact of an anthropogenically transformed environment on the content of pharmaceutically valuable biologically active compounds in medicinal plants is analyzed. The studied biologically active substances included phenolic compounds (flavonoids, anthocyanins, tannins, and phenolic acids). The number of transmissible forms of heavy metals (HMs), including cadmium, lead, and mercury, were discharged from factories that are present in the soil. Plants uptake these toxic metals from the soil. HM causes changes in the activity of the several enzymes such as phenylalanine ammonia lyase (PAL), chalcone synthase (CHS), chalcone isomerase (CHI) and other enzymes. These enzymes play an important role in biosynthesis of phenolic compounds in medicinal plants. It has been demonstrated that plant materials possess high antioxidant potential due to their high phenolic content. As a result, the present review discusses a thorough investigation of anthropogenically transformed environment effects on the quantity of pharmaceutically valuable phenolic compounds in medicinal plants.