P31 A novel disease endotype in SLE characterized by B cell hyperactivity, Sm/RNP reactivity and higher disease activity

• Cynthia Aranow,
• Meggan Mackay,
• Betty Diamond,
• Tom WJ Huizinga,
• Annemarie L Dorjée,
• René EM Toes,
• Jolien Suurmond,
• Yemil Atisha-Fregoso,
• Hugo J van Dooren

Affiliations

Cynthia Aranow

2The Feinstein Institutes for Medical Research, Manhasset, NY, USA

Meggan Mackay

The Center for Autoimmune & Musculoskeletal Disease, The Feinstein Institute for Medical Research, Manhasset, New York, USA

Betty Diamond

Institute of Molecular Medicine, Feinstein Institutes for Medical Research, Manhasset, New York, USA

Tom WJ Huizinga

Rheumatology, Leiden University Medical Center, Leiden, The Netherlands

Annemarie L Dorjée

1 Rheumatology, Leiden University Medical Center, Leiden, The Netherlands

René EM Toes

Rheumatology, Leiden University Medical Center, Leiden, The Netherlands

Jolien Suurmond

1Department of Rheumatology, Leiden University Medical Centre, Leiden, The Netherlands

Yemil Atisha-Fregoso

Institute of Molecular Medicine, Feinstein Institutes for Medical Research, Manhasset, New York, USA

Hugo J van Dooren

1Dept.t of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands; Center for autoimmune, musculoskeletal and hematopoietic diseases