Сахарный диабет (Jun 2011)
Serum lipid profile in native populations (evens, nanais, ulchis) of the Amur region diagnosed with type 2 diabetes mellitus
Abstract
Aim. To determine serum lipid profile in native populations (Evens, Nanais, Ulchis) of the Amur region diagnosed with type 2 diabetes mellitus. Materials and methods. 297 Evens, 792 Ulchis, and 1,274 Nanais aged 30-70 years and older were examined. Total cholesterol, triglyceride, andhigh-density lipoprotein were measured with a Sapphire autoanalyzer (Japan) using Olveks Diagnosticim enzymatic kits (including reference sera).LDL levels were calculated by W.Fridewold formula (TC-HDL-TG/2.2) in millimol/l. Glucose tolerance test to verify type 2 DM was performed withthe measurement of blood glucose level by the glucose oxidase method. Previously diagnosed DM2 was taken into account. The results were estimatedbased on WHO criteria (1999). The study was carried out in winter time. Conclusion. Changes of the serum lipid profile in DM2 female aborigines of the Amur region were consistent with the literature data. Specifically, theyshow higher TC, TG,, HDL and lower LDL levels compared with DM-free women of the same population. The lowest levels of TC, TG, HDL, andLDL were documented in female Evens. Nanais and Ulchis with DM2 had similar lipid profiles.
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