Безопасность и риск фармакотерапии (Feb 2018)
Combined oral contraceptives: evolution of the relationship benefit/risk
Abstract
Currently, more than 100 million women worldwide use combined oral contraceptives. Risk/benefit ratio of this group of drugs over the half-century history is largely changed in the direction of safety. The factors that increase the safety of this group of drugs, as well as the main risk factors are discussed.