IMMUNOLOGICAL FUNCTION OF INTESTINAL MICROFLORA, ITS ABNORMALITIES AND POSSIBILITIES OF CORRECTION

Abstract

The review presents current data indicating that normal microflora plays an important role in the development of intestinal immune system. Intestinal microorganisms stimulate maturation of intestinal lymphoid tissue, synthesis of secretory immunoglobulin A, activate phagocytosis, stimulate the cytokine and interferon system. Of interest is the discussion of tolerance phenomenon which is highly significant for formation of a stable micro-biocenosis. Probiotics are increasingly used for controlled formation or restoration of abnormal micro-biocenosis. Confirmation of the useful properties of every strain of a probiotic culture in controlled clinical trials is recognized as one of the key requirements to probiotics.

Keywords

• lymphoid tissue
• dendrite cell
• macrophage
• type of immune reactions
• immunoglobulin
• normal microflora
• dysbacteriosis
• probiotics