Conductive nanomaterials for cardiac tissues engineering

Abstract

Myocardial infarction (MI) is a worldwide disease with high incidence and high fatality rate. In the past decade, a lot of research work based on the method of cardiac tissues engineering has received wide attention from researchers and has been demonstrated to have important application prospects in the treatment of MI. To make engineered cardiac tissue (ECTs) simulate the characteristics of the natural myocardial microenvironment better, the unique electrophysiological characteristics of myocardial tissue should be considered. Therefore, conductive nanomaterials are adopted to construct ECTs to make up for the lack of traditional scaffold materials. In this article, the research progresses of conductive nanomaterials application in the field of cardiac tissue engineering are summarized, and two treatment strategies of cardiac patch construction and injectable materials for MI treatment are discussed respectively. Related research work provided reference for the study of cardiac tissue engineering based conductive nanomaterials.

Keywords

• Myocardial infarction
• Cardiac tissues engineering
• Biomaterial
• Nanomaterials