A mass event of paraquat poisoning via inhalation

Mengdi Shi; Mengdi Shi; Mei Zeng; Tianzi Jian; Guangcai Yu; Aerbusili Genjiafu; Aerbusili Genjiafu; Xiangxing Zhang; Xiangxing Zhang; Lanlan Guo; Lanlan Guo; Ruikai Shang; Ruikai Shang; Zhiqiang Zhou; Zhiqiang Zhou; Tongyue Zhang; Xiangdong Jian; Xiangdong Jian; Baotian Kan; Baotian Kan

doi:10.3389/fpubh.2023.1309708

Frontiers in Public Health (Dec 2023)

A mass event of paraquat poisoning via inhalation

Mengdi Shi,
Mengdi Shi,
Mei Zeng,
Tianzi Jian,
Guangcai Yu,
Aerbusili Genjiafu,
Aerbusili Genjiafu,
Xiangxing Zhang,
Xiangxing Zhang,
Lanlan Guo,
Lanlan Guo,
Ruikai Shang,
Ruikai Shang,
Zhiqiang Zhou,
Zhiqiang Zhou,
Tongyue Zhang,
Xiangdong Jian,
Xiangdong Jian,
Baotian Kan,
Baotian Kan

Affiliations

Mengdi Shi: Department of Occupational and Environmental Health, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China
Mengdi Shi: Department of Poisoning and Occupational Diseases, Emergency Medicine, Cheeloo College of Medicine, Qilu Hospital of Shandong University, Shandong University, Jinan, Shandong, China
Mei Zeng: Department of Poisoning and Occupational Diseases, Emergency Medicine, Cheeloo College of Medicine, Qilu Hospital of Shandong University, Shandong University, Jinan, Shandong, China
Tianzi Jian: Department of Hematology, Qilu Hospital of Shandong University, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China
Guangcai Yu: Department of Poisoning and Occupational Diseases, Emergency Medicine, Cheeloo College of Medicine, Qilu Hospital of Shandong University, Shandong University, Jinan, Shandong, China
Aerbusili Genjiafu: Department of Occupational and Environmental Health, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China
Aerbusili Genjiafu: Department of Poisoning and Occupational Diseases, Emergency Medicine, Cheeloo College of Medicine, Qilu Hospital of Shandong University, Shandong University, Jinan, Shandong, China
Xiangxing Zhang: Department of Occupational and Environmental Health, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China
Xiangxing Zhang: Department of Poisoning and Occupational Diseases, Emergency Medicine, Cheeloo College of Medicine, Qilu Hospital of Shandong University, Shandong University, Jinan, Shandong, China
Lanlan Guo: Department of Occupational and Environmental Health, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China
Lanlan Guo: Department of Poisoning and Occupational Diseases, Emergency Medicine, Cheeloo College of Medicine, Qilu Hospital of Shandong University, Shandong University, Jinan, Shandong, China
Ruikai Shang: Department of Occupational and Environmental Health, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China
Ruikai Shang: Department of Poisoning and Occupational Diseases, Emergency Medicine, Cheeloo College of Medicine, Qilu Hospital of Shandong University, Shandong University, Jinan, Shandong, China
Zhiqiang Zhou: Department of Occupational and Environmental Health, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China
Zhiqiang Zhou: Department of Poisoning and Occupational Diseases, Emergency Medicine, Cheeloo College of Medicine, Qilu Hospital of Shandong University, Shandong University, Jinan, Shandong, China
Tongyue Zhang: Department of Poisoning and Occupational Diseases, Emergency Medicine, Cheeloo College of Medicine, Qilu Hospital of Shandong University, Shandong University, Jinan, Shandong, China
Xiangdong Jian: Department of Occupational and Environmental Health, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China
Xiangdong Jian: Department of Poisoning and Occupational Diseases, Emergency Medicine, Cheeloo College of Medicine, Qilu Hospital of Shandong University, Shandong University, Jinan, Shandong, China
Baotian Kan: Department of Nursing, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China
Baotian Kan: Department of Gerontology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China

DOI: https://doi.org/10.3389/fpubh.2023.1309708
Journal volume & issue: Vol. 11

Abstract

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ObjectiveIn January 2023, a rare event of collective inhalation paraquat poisoning occurred in Shandong, China. To analyze the clinical characteristics of an event of respiratory tract paraquat poisoning through inhalation.MethodsClinical data from eight patients with paraquat inhalation poisoning were retrospectively analyzed.ResultsThe patients were mainly exposed to paraquat via the respiratory tract. The main clinical manifestations were ocular and respiratory irritation. Lung computed tomography (CT) showed that all eight patients had varying degrees of lung injury, mainly manifesting as exudative lesions. Laboratory tests revealed arterial blood gas hypoxemia, abnormal white blood cell count, and increased neutrophil ratio. Sufficient glucocorticoid impact therapy was effective, and all eight patients survived.ConclusionEight patients experienced chest tightness, shortness of breath, and varying degrees of lung injury due to inhalation of paraquat through the respiratory tract. The early use of glucocorticoids and other comprehensive treatment measures, active prevention and treatment of lung infections, and protection of organ function have beneficial effects in such cases.

Published in Frontiers in Public Health

ISSN: 2296-2565 (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Medicine: Public aspects of medicine
Website: https://www.frontiersin.org/journals/public-health

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