Sleep Science (Sep 2014)

Restless leg syndrome exacerbated by amytriptiline in a patient with Duchenne Muscular Dystrophy

  • Ricardo Tera Akamine,
  • Luis Fernando Grossklauss,
  • Karen Tieme Nozoe,
  • Gustavo Antonio Moreira,
  • Acary Souza Bulle Oliveira,
  • Marco Antônio Troccoli Chieia,
  • Monica Levy Andersen,
  • Sergio Tufik

DOI
https://doi.org/10.1016/j.slsci.2014.09.010
Journal volume & issue
Vol. 7, no. 3
pp. 178 – 180

Abstract

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We report an unusual case of a Duchenne Muscular Dystrophy(DMD) patient who initiated a restless leg syndrome after the use of amytriptiline. The prescription and use of this medication for patients with persistent neuropathic pain is relatively common, especially for patients with DMD. Normally, this medication is well tolerated, however, we now report the occurrence of an induction or intensification of a restless leg syndrome case in a young patient with DMD, treated with amytriptiline for his chronic pain.

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