Predictors of cardiovascular risk in metabolic syndrome carriers

Abstract

Introduction: Metabolic syndrome is a predictor of cardiovascular morbidity and mortality; habits and lifestyles are important in its expression, in its etiology, progression and complications. The search for better risk predictors, since cardiovascular disease is the first cause of death in Cuba and the world, is a priority for health services. Objective: Characterize predictors of cardiovascular risk in carriers of metabolic syndrome. Methods: A cross-sectional descriptive observational study was carried out in 60 patients, older than 45 years, with a diagnosis of metabolic syndrome and the presence of 4 diagnostic criteria. The study variables were: levels of triglycerides, cholesterol, ApoA, ApoB and the atherogenic indices ApoB/ApoA, ApoB/total cholesterol. Results: There was an increase in proatherogenic predictors, reflected in TG levels (above 1.7 mmol/L), ApoB 100 (1.42 g/L) and a decrease in antiatherogenic markers with ApoA 1 values (1.0 g/L) and the ApoB 100/ApoA 1(0.5 Decile) ratio somewhat far from the 1 Decile value, established as the reference value and a high risk of cardiovascular disease when the ApoB/total cholesterol ratio is found (0.73 g/L) above normal values. Conclusions: Apolipoproteins and atherogenic indices are better predictors of cardiovascular risk by expressing the balance between plasma pro- and anti-atherogenic particles, as well as the formation of atheromatous plaque precursors.

Keywords

• síndrome metabólico
• predictores de riesgo
• riesgo cardiovascular.