Research progress of Apelin in female reproductive health

Abstract

Apelin is an adipokine family which includes Apelin-13, Apelin-36 and other isoforms and regulates physiological functions by immunomodulation, oxidative stress, glycolipid metabolism, and apoptosis and so on. Apelin is closely related to polycystic ovary syndrome, ovarian cancer and other diseases of the female reproductive system so it is expected to be new target molecules and may orient the development of research and clinical treatment.

Keywords

• apelin|ovary|granulosa cells|adipokine|endometrium