Effect of eight weeks of HIIT training on serum levels of C1q/TNF5, insulin resistance, and fat percentage in overweight women

Abstract

Purpose: C1q/TNF5 is a new adipokine that plays an important role in the metabolism of glucose and lipids. High-intensity interval training (HIIT) is a form of interval training, alternating short periods of intense anaerobic exercise with the less-intense recovery period. The aim of this study was to evaluate the effect of eight weeks of HIIT training on serum levels of C1q/TNF5, insulin resistance, and fat percentage in overweight women.Methods: The research method was semi-experimental with pre-test and post-test design. 28 overweight and inactive women were randomly assigned to two equal groups, control group (age 30.142±3.526 and BMI 28.742±0.882 kg/m2) and HIIT group (age 29.928±2.758 years and BMI 28.147±1.126 kg/m2). The HIIT group performed interval running with the maximum speed, three times per week for eight weeks. Blood sampling was done 24 hours before and 36 hours after the training. The blood serum was used for the measurement of C1q/TNF5 level and insulin resistance. Data were analyzed by paired t-test and independent t-test (P0.05) remained with no significant changes.Conclusion: It seems that HIIT training can be a useful way to reduce overweight and obesity complication by decreasing the serum levels of C1q/TNF5 and insulin as well as the body fat percentage.

Keywords

• c1q/tnf5
• fat percentage
• high-intensity interval training
• insulin resistance
• overweight