Гинекология (Aug 2014)

Diagnosis and treatment of vaginal microbiome: Is it all that simple?

  • N I Chernova,
  • Yu N Perlamutrov,
  • I S Petrova

Journal volume & issue
Vol. 16, no. 4
pp. 7 – 11

Abstract

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Changes in microbiome of the genital tract in the absence of obligate pathogens are manifested in the increasing number of opportunistic pathogens, contamination of the unusual for this type of bacterial habitats and reducing of the amount of normal flora, particularly lactobacilli. The aim of the study was to improve the efficiency of the therapy of vaginal microbiome by topical application of Gynoflor E, which is the basis of Lactobacilus acidophilus lyophilisate 50 mg (at least 100 million of viable bacteria) and 0,03 mg estriol. The study involved 120 sexually active women of reproductive age (18-45 years) complaining of discomfort in the vagina, and excretion. The drug is used by 1 vaginal tablet at night №12 the course. The results showed that the inclusion of Gynoflor E in standard methods of therapy of microbiome of the lower genital tract contributed to significant increase in the effectiveness of treatment to 86% instead of 46-53% when using only antibiotic therapy.

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